Mawra Hocane was born in Karachi but she grew up in Islamabad where her family was moved and where she completed her pre-medical education from Bahria College. She is currently studying LL.B. at the University College of Islamabad. She is the sister of television actress Urwa Hocane. Mawra changed the spelling of her family name from "Hussain" to "Hocane" in 7th grade class to give it a unique spelling.